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Going from the inside to the outside, we find a microclimate consisting of the unstirred water layer, glycocalyx, and mucus layer which prevent bacterial adhesion by physical barrier provided by the glycocalyx and mucus and by the secretion of antimicrobial proteins (AMPs) and immunoglobulin A (IgA)

This highlighted the urgent need for novel therapeutic approaches that aims at preventing and/or reversing its sequelae (Zhao et al., 2018)

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Back then all we really knew about this supplement was that it improved angina, heart function, and exercise tolerance in patients with coronary artery disease and heart failure